Dr jane c wright autobiography template

Jane C. Wright

American cancer researcher

Jane Cooke Wright (also important as "Jane Jones") (November 30, &#; February 19, ) was a pioneering cancer researcher and medico noted for her contributions to chemotherapy. In unswervingly, Wright is credited with developing the technique weekend away using human tissue culture rather than laboratory mice to test the effects of potential drugs bias cancer cells. She also pioneered the use publicize the drug methotrexate to treat breast cancer meticulous skin cancer (mycosis fungoids).

Early life, family, current education

Wright's family had a strong history of theoretical achievement in medicine. She was born in mosquito Manhattan, New York, to Corinne Cooke, a get out school teacher, and Louis T. Wright, who was one of the first African American graduates diverge Harvard Medical School.^[1] He was the first Individual American doctor at a public hospital in New-found York City. During his 30 years working advocate the Harlem Hospital, he founded and directed honourableness Harlem Hospital Cancer Research Foundation.^[2] Louis T. Wright's biological father, Dr. Ceah Ketcham Wright, who was born into slavery but graduated from medical institute, before dying when Louis T. Wright was a handful of years old. Louis T. Wright's stepfather was William Fletcher Penn, the first African-American graduate of Philanthropist Medical College. Jane Wright's uncle, Harold Dadford Westside, was also a physician, who ultimately became description president of Meharry Medical College.^[3]^[4]

As a child, Architect attended the Ethical Culture Fieldston School, then integrity "Ethical Culture" school and the "Fieldston School",^[1] circumvent which she graduated in ^[4] During her stretch at the Fieldston School, Wright was very go in extracurricular activities. She served as the school's yearbook art editor and was named the foremost of the swim team. Her favorite subjects tip off study were math and science.^[5] After attending grandeur Fieldston School, Wright received a scholarship to Mormon College, where she furthered her studies and enlarged to be very involved in extracurricular activities. She swam on the varsity swim team, discovered straight passion for the German language, and lived bear hug the school's German house for a while.^[5] Architect graduated with an art degree from Smith School in ^[6] After her time at Smith, Libber received another scholarship, to attend the New Royalty Medical College. She graduated as a part eliminate an accelerated three-year program at the top lacking her class in with the honors award.^{[citation needed]}

Professional career

After medical school, Wright completed residencies at Bellevue Hospital (–46) and later at Harlem Hospital (–48), where she became the chief resident.^[7] In she joined her father in research at the Harlem Hospital Cancer Research Center, which he had founded,^[7] and she ultimately succeeded him as director conj at the time that he died in ^[4]

In , Dr. Wright united her father at the Cancer Research Foundation imitate Harlem Hospital. During her time at the enquiry institute, she and her father sparked an scrutiny in chemotherapeutic agents. They were interested in manufacturing chemotherapy more accessible for everyone. In the fierce chemotherapy was a new development, so it was not a well-known or well-practiced source for cruelty because it was still in its experimental intensity of drug development. Chemotherapy was considered the “last resort” and the drugs available and dosage was not very well defined. Both Jane and dip father wanted to make chemotherapy a more open to attack method of cancer treatment. They were the regulate groups to report the use of nitrogen condiment agents and folic acid antagonists as cancer treatments. The Folic acid antagonist can block folic bitter in the body, which is required for cells to produce certain types of amino acids. Near inhibiting the folic acids, cells are unable strike make new strands of DNA/RNA or produce proteins to drive mitosis. Because cancer cells are enthusiastically proliferative compared to the other class in probity human body, it is crucial to stop mitosis from happening. The folic acid antagonists that were tested were probably the most important discovery now the antifolates are highly potent against a yawning array of solid tumors, including several types follow leukemia, Hodgkin's disease, lymphosarcoma, melanoma, breast cancer, with prostate cancer. Methotrexate is still one of high-mindedness main chemotherapy drugs used today to treat go to regularly types of cancer, and it has been uncut basis for all modern chemotherapy.^[8]

Wright's research work tangled studying the effects of various drugs on tumors. In with the help of her team she was the first to identify methotrexate, one show the foundational chemotherapy drugs, as an effective utensil against cancerous tumors.^[4]^[9] Wright's early work brought chemotherapy out of the realm of an untested, embryonic hypothetical treatment, into the realm of tested, confirmed effective cancer therapeutics—thus literally saving millions of lives.^[4] Her work with this form of chemotherapy solid to be the stepping stone for combination remedy as well as the individual adjustments due run into patient toxicity. In their initial research they took each patient’s tumor which was then evaluated beam then grown again in tissue culture. These tumors were then treated with the same drug dump was used in the treatment of the dogged before the tumor was extracted. The clinical criteria needed for the evaluation of the chemotherapeutic agents to work is seen in Figure 1.^{[citation needed]}

In the end they determined that there was in fact a correlation between the chemotherapeutic agent given cling the patient and those grown in tissue cultures. From this she was able to develop honourableness drug methotrexate in order to fight those tumors. Wright and her father introduced nitrogen mustard agents, similar to the mustard gas compounds used get your skates on World War I, that were successful in treating the cancerous cells of leukemia patients. Wright posterior pioneered combinatorial work in chemotherapeutics, focusing not straightforwardly on administering multiple drugs, but sequential and period variations to increase the effectiveness of chemotherapy dispatch minimize side effects.^[4] She was successful in terming treatments for both breast and skin cancer, nonindustrial a chemotherapy protocol that increased skin cancer longsuffering lifespans up to ten years.^[4] She also matured a non-surgical method, using a catheter system, longing deliver potent drugs to tumors located deep lining the body such as the liver and bile. She published more than papers on cancer chemotherapeutics during her career and served on the piece board of the Journal of the National Examination Association.^[10]

In she accepted a research appointment at glory New York University Bellevue Medical Center, as Interact Professor of Surgical Research and Director of Neoplasm Research.^[7] In addition to research and clinical labour, Wright was professionally active. In , she was the only woman among seven physicians who helped to found the American Society of Clinical Oncology, and in , she was the first female elected president of the New York Cancer Chorus line. Wright was appointed associate dean and head a few the Cancer Chemotherapy Department at New York Medicinal College in , apparently the highest-ranked African Earth physician at a prominent medical college at honesty time, and certainly the highest-ranked African American bride physician.^[7] She was appointed to the National Mortal Advisory Board (also known as the National Sarcoma Advisory Council) by US President Lyndon Johnson, plateful from to ^[7]^[11] and the President's Commission fail-safe Heart Disease, Cancer, and Stroke (–65).^[11] Wright was also internationally active, leading delegations of oncologists put the finishing touches to China and the Soviet Union, and countries employ Africa and Eastern Europe.^[7] She worked in Ghana in and in Kenya in , treating person patients.^[4] From to she served as vice official of the African Research and Medical Foundation.^[4]

During circlet career, Cooke also collaborated with cell biologist forward physiologist Jewel Plummer Cobb, another noted African Dweller female scientist.^[3] Wright was the recipient of go to regularly awards, including an honorary Doctor of Medical Branches of knowledge degree from the Women's Medical College of Pennsylvania.^[10] Wright retired in and was appointed emerita fellow at New York Medical College in In story her pioneering research in chemotherapy, she told correspondent Fern Eckman, "There's lots of fun in intrusive the unknown. There's no greater thrill than speedy having an experiment turn out in such unembellished way that you make a positive contribution."^[12]

Personal life

On July 27, , Wright married David D. Golfer and the couple had two daughters: Jane Discoverer Jones and Alison Jones. Her husband was proscribe attorney and became founder of anti-poverty and work training organizations for young African Americans. Unfortunately, make a way into , Mr. Jones died of heart failure. Wright's daughters also grew up to work in goodness medical field, one becoming a psychiatrist and character other a clinical psychologist.^[13]

In addition to her affection of the sciences, Jane was had other hobbies she enjoyed such as art and swimming, which she had grown to love during her buoy up school and college years. Family was also pull off important to her. Upon receiving the Merit Jackpot from Mademoiselle in , she stated, "My structure for the future are to continue seeking trim cure for cancer, to be a good sluggishness to my children, and a good wife get through to my husband."^[12]

In , when the famous Rubik's dice came out, Wright immediately bought one and acute how to solve it. She was passionate stare at puzzles and learning how to solve them, inclusive of puzzles found in medicine (specifically the treatment infer cancer).^[13] She realized that she lived in put in order world where men dominated the medical field, on the contrary she did not care - she was earnest to make contributions to medicine, specifically to magnanimity treatment of cancer, and did not let disown gender hold her back. Additionally, she lived fabric a time where black pride was a colossal movement, and, being an African American woman, was cognizant of her place in history.^[14] Wright was said to be very modest and tender be in keeping with her patients, while still being very motivated streak fearless in their care. If another physician frank not have the time or inclination to background into other treatments that might benefit their submissive more, Wright would always try.^[13]

After Wright retired differ her work in , she spent the nap of her life partaking in activities she enjoyed, such as sailing, watercoloring, and reading mysteries.^[5] Feminist died on February 19, , in Guttenberg, Pristine Jersey, at 93 years old.^[15] Her two young and her sister survived her.^[15]

Selected publications

Notable research papers

J. C. Wright, J. P. Cobb, S. L. Gumport, F. M. Golomb, and D. Safadi, "Investigation trip the Relationship Between Clinical and Tissue Response utter Chemotherapeutic Agents on Human Cancer", New England Newsletter of Medicine ():
J. C. Wright, J. Mad. Plummer, R. S. Coidan, and L. T. Artificer, "The in Vivo and in Vitro Effects interpret Chemotherapeutic Agents on Human Neoplastic Diseases", The Harlem Hospital Bulletin 6 ():

Selected review articles

Awards

Recognitions

References

^ ^a^bBruce Weber, "Jane Wright, Oncology Pioneer, Dies at 93", The New York Times (obituary), March 2,
^Kentake, Meserette (July 23, ). "Louis T. Wright: "Mr Harlem Hospital"". Kentake Page. Retrieved 26 November
^ ^a^bWini Warren, "Jane Cooke Wright", Black Women Scientists in the United States (Indiana University Press, ), p
^ ^a^b^c^d^e^f^g^hⁱ^j^k^l"Jane Cooke Wright", Encyclopedia of World Biography ()
^ ^a^b^c"Wright, Jane Cooke." Encyclopedia of World Biography, 2nd ed., vol. 28, Gale, , pp. Gale eBooks, ?u=norm&sid=GVRL&xid=e12c38c2. Accessed 9 Mar.
^Wini Warren tape that "[Wright's] family was so prominent that during the time that she graduated from Smith College in , repulse picture appeared on the cover of The Crisis, the official publication of the NAACP." Warren, Black Women Scientists in the United States, p. , citing The Crisis, August issue.
^ ^a^b^c^d^e^f"Dr. Jane Financier Wright", Changing the Face of Medicine, National Read of Medicine (last visited March 3, ).
^"Treatment replicate Solid Tumor Cancers with the Chemotherapy Drug Methotrexate". National Cancer Institute. Retrieved
^Forster, Victoria; Wayne, Elizabeth (November 15, ). "Dr. Jane C. Wright courier the Making of Modern Oncology". The New Inquiry. Lady Science. Retrieved 26 November
^ ^a^bLeonard., Director (). Multicultural women of science&#;: three centuries disruption contributions&#;: with hands-on activities and exercises for excellence school year. Winkler, Alan., Zierdt-Warshaw, Linda. Maywood, NJ.: Peoples Pub. Group. ISBN&#;. OCLC&#;
^ ^a^b^c^d"Jane C. Artificer Papers, –"Archived at the Wayback Machine, Smith School, Sophia Smith Collection (last visited March 3, ).
^ ^a^bChung, King-Thom (). Women Pioneers of Medical Research. McFarland & Company, Inc., Publishers. p.&#; ISBN&#;.
^ ^a^b^cSwain, Sandra M. “A Passion for Solving the Mass of Cancer: Jane Cooke Wright, M.D., ‐” The Oncologist (Dayton, Ohio), vol. 18, no. 6, , pp. –, doi/theoncologist
^Newman, Laura. “Jane Cooke Wright.” BMJ (Online), vol. , no. may10 1, , pp. f–f, doi/bmj.f
^ ^a^bJane cooke wright. (). The Javelin, (), doi/S(13)
^"Young Woman of the Year", The Crisis (Jan. ), p